With a vast knowledge base in molecular biology and bioinformatics, I am deeply passionate about integrating hands-on laboratory expertise with advanced data analysis techniques. I aspire to contribute significantly towards innovative and transformative discoveries through OMICs and establishing new collaborations within biological research. My career goal is to continually bridge the gap between experimental exploration and insightful data analysis, thus shaping the future of scientific research.
I am a Junior Researcher at CINTESIS (Universidade do Algarve, Portugal).
Research Interests | I use Computational Biology as a way of answering biologically relevant questions. My research interests are focused on understanding how gene expression profiles translate into robust genetic modules that explain the phenotypic plasticity observed in healthy and diseased cells, particularly cancer. I am passionate about Open Science and I am always keen on establishing new collaborations.
Current Project | I am starting my independent research line studying cancer causality using Structural Causal Models.
Previous Research | I have experience with OMICs datasets, which I have used to study breast cancer, genetic regulation in early vertebrate embryo development, in stem cell differentiation, and in mitochondrial evolution.
Teaching | I teach Computational Biology at the Universidade do Algarve, and I organize yearly courses on R programming.
Expertise | Cancer genetics, Molecular oncology, R programming (including package development), OMICS data analysis.
Subham Preetam is the Founder & CEO of N BASE. He is a professional biotechnologist in the field of biorobotics, cancer, immunity, biomedical, and nanometerial research. He is dedicated to the advancement of precision medicine and successful preclinical research to enhance the quality of life for individuals.
With extensive cross-disciplinary training and experience in translational research, he is currently focused on various research topics, including microrobotics, soft bio-hybrid robots, and quantum nanoparticles for drug delivery. His research aims to improve the life expectancy of sea animals and humans.
Furthermore, he is involved in developing a bio-fluidics nanomedicine system that leverages the latest drug delivery technologies to create personalized solutions for brain cancer patients in South Korea and Sweden. Additionally, he collaborates with researchers from India, Taiwan, Israel, US, Denmark, Singapore, Spain, Portugal, and the United Kingdom on various collaborative projects.
I am a Professor of Toxicology, Biochemistry and Cell Signaling at Université Paris Cité (former Université Paris Descartes). I have completed my PhD in molecular toxicology and a post-graduate year in Bethesda, MD. I am the head of a Master degrees in toxicology and ecotoxicology. My research is based on cellular and animal models and on three main axes: 1) the influence of persistent organic pollutants on breast tumorigenesis and metabolic disruption, 2) the contextual role of pollutants in the occurrence of chronic liver diseases including steatosis and fibrosis, 3) the effect of mixtures on the progression of neurodegenerative diseases. I am involved in the development of innovative pedagogy methods and technics in order to improve transmission, acquisition, memorization and utilization of scientific knowledge by our biomedical students. I used flipped classrooms, quizzes (at home and during courses) and virtual reality to interact and immerge with students in and outside the classroom. Indeed, I developed with pedagogic engineers, 1) Home-based 45’’ Quizzes to engage students in regular learning modes and 2) serious games on cell signaling and xenobiotic stress. Together, with Etienne Blanc, Caroline Chauvet and Frédéric Dardel, I wrote several French books of biochemistry and toxicology topics for undergraduate students. I collaborate with several national and international institutes and universities (CNAM Thierry KOSCIELNIAK, Université de Strasbourg Jean-Luc SOUCIET, National University of Singapore, Fun Man FUNG...) for the development of innovative methods in teaching.
Matrix Pathobiology, Extracellular Matrix, Matrix-mediated cell regulation and singaling, Pharmacological targeting, Biochemical Assays, Proteoglycans, Glycosaminoglycans, Metalloproteinases
Paraoxonase-1, glucagons like peptide-1 receptor, G-proteins, molecular interactions, enzyme kinetic, signalling, neurodegenerative diseases, diabetes mellitus 2, technology for teaching and learning
Dr. Isabel Varela-Nieto graduated and earned her doctorate in Chemistry, Biochemistry Section, at the University Complutense of Madrid (Spain). She has been a visiting guest scientist at the Medical Schools of Uppsala (FEBS Fellow, Sweden) and San Diego (MEC Sabbatical, USA). She is Professor of Research at the CSIC and group leader at the CIBER of rare diseases (CIBERER, ISCIII) in Madrid. From the early 1990s she has been studying hearing neurobiology and IGF-1 actions. She was the first Chair of the SEBBM Science for Society working group with which she actively collaborates, and member of the FEBS Network working group. She is currently the president of the SEBBM, a member of the FEBS Science and Society Committee and of the ISC Finances Committee.