My research interests focus on the roles mitochondria play in aspects of eukaryotic life, ranging from their origin, metabolism, biogenesis and role they play in cell death pathways. These are interrogated using biochemical, molecular biology, genetic and cell biology techniques. I incorporate these interests into classes I teach to provide an understanding of practical techniques and also the current literature in the field. I studied biochemistry at the University of Leeds, with an industrial placement at Astra Charnwood, followed by a PhD at the University of Bristol, supervised by Professor Andrew Halestrap, to characterise the molecular composition of the mitochondrial permeability transition pore, with support from MitoKor. My post-doctoral training on the mitochondrial pathway of apoptosis supervised by Dr Doug Green was at the La Jolla Institute of Allergy and Immunology in San Diego, California and St Jude Children's Research Hospital in Memphis, Tennessee. I then was an associate research scientist working in the laboratory of Professor Alexander Tzagoloff at Columbia University in New York to study biogenesis of mitochondrial cytochrome c oxidase in budding yeast, Saccharomyces cerevisiae. I held independent positions as assistant professor at the New York Institute of Technology in New York and Staffordshire University in Stoke-on-Trent where I continued my research and taught subjects related to biochemistry, cell biology, genetics and molecular biology. I am now a senior lecturer in biotechnology at Liverpool John Moores University. I am a strong supporter of scientific communications and outreach to disseminate scientific developments and knowledge to a broader audience with the goal of increasing the general support of the scientific process. I also direct Biomed News, a free biomedical research literature discovery platform that uses machine learning.
MSc in Bacterial Physiology and PhD in Protein Biochemistry
Professor (Associate) at Akdeniz University
Structural and functional analysis of rat prolactin receptor gene. Rat prolactin receptor and isoforms in liver and kidney. Non-genotoxic toxicity and tumorigenesis mechanisms of ochratoxin A (OTA) in vivo and in vitro. The role of testosterone and estrogen in OTA toxicity. The receptor mediated OTA toxicity and tumorigenesis in rat kidney.
Ochratoxins
Prolactin Receptors
Estrogen Antagonists
Estrogen Receptor
Testosterone
Androgen Receptors
Nonsteroidal Anti-Androgens
Ovariectomy
Castration
mRNA Expression
Renal Pathology
Renal Cancer
Targeted Drug Delivery
Toxicity
Endocrine Disruption
Reproductive Toxicology
Estrogens
Cancer Biology
Androgens
Steroids
Toxicity Studies
Native PAGE
Endocrine Disruptors
Environmental Toxicology
Animal Physiology
Encapsulation
Cancer Research
Nanoparticles
Microbiology
Biotechnology
Proteins
Protein Stability
Ions
Mycotoxins
Cancer Cell Biology
Fluorescence Spectroscopy
Site-Directed Mutagenesis
Wistar Rats
Protein Folding
Circular Dichroism
Protein Conformation
Cell Culture
Molecular Endocrinology
Neuroendocrinology
Biomarkers
PCR
Protein Purification
Reproductive Endocrinology
Protein Structure
Protein-Protein Interaction
I am the FEBS Events Associate – Advanced Courses, Congress, 3+ at FEBS, supporting the delivery of those events. Previously I was the Communications and Digital Platforms Associate, also at FEBS, and worked on platforms such as the FEBS Network and FEBS website.
Before joining FEBS I managed the grant programmes of a number of UK research charities, mainly in the field of cancer, as well as supported the fundraising at those organisations. I also developed e-learning resources at the Institute of Cancer Research. I have a BSc in Biochemistry and an MSc in Nutrition. After years in London I have now moved back to Spain.
I'm a second-year Ph.D. student working on tissue engineering and regenerative medicine. interested in tissue engineering and biotechnologies as well as cancerology. I had a hand-on experience on many molecular, cell culture, IHC and staining techniques.
Dr. Isabel Varela-Nieto graduated and earned her doctorate in Chemistry, Biochemistry Section, at the University Complutense of Madrid (Spain). She has been a visiting guest scientist at the Medical Schools of Uppsala (FEBS Fellow, Sweden) and San Diego (MEC Sabbatical, USA). She is Professor of Research at the CSIC and group leader at the CIBER of rare diseases (CIBERER, ISCIII) in Madrid. From the early 1990s she has been studying hearing neurobiology and IGF-1 actions. She was the first Chair of the SEBBM Science for Society working group with which she actively collaborates, and member of the FEBS Network working group. She is currently the president of the SEBBM, a member of the FEBS Science and Society Committee and of the ISC Finances Committee.