From bacteria to eukaryotes, cells have evolved a remarkable battery of enzymes to deal with the mechanical and topological challenges presented by nucleic acid production, processing and maintenance. A clear view of the biology of the genetic material requires a molecular understanding of how these enzymes function. Such an understanding will enhance our ability to manipulate genome structure and gene expression. The theme of this meeting revolves around the mechanisms of these enzymes, with particular emphasis on research that integrates structural, biochemical, biophysical and computational approaches. With recent technological advances in imaging (i.e., single-molecule and cryo-electron microscopies), we expect to witness a flourish of key biological systems to be characterised with unprecedented detail.
This meeting will cover many of the molecular mechanisms by which large macromolecular machines carry out a diverse range of nucleic acid processes including DNA replication and repair, gene transcription and regulation, RNA processing and splicing, translation, nucleic acids structures and chromatin structure and epigenetic mechanisms. The meeting will also explore new quantitative techniques as well as theoretical approaches.
Invited speakers include:
- Keynote speaker - John Diffley, The Francis Crick Institute (UK)
- Keynote speaker - Rachel Green, Johns Hopkins University (USA)
- Colworth Medal Lecture - Stephan Uphoff, University of Oxford (UK)
Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.
For the full program and other event details, please visit the event website at https://www.eventsforce.net/86hardenconference
The FEBS3+ Meetings programme was established by FEBS to support scientific meetings, organised through collaboration of at least three FEBS Constituent Societies. The aim of the programme is to increase international collaboration between molecular life scientists in a subset of countries within the FEBS area, while also encouraging sharing of expertise and efforts. These events are generously supported by FEBS.
For this meeting, a FEBS3+ travel award scheme is also available to young scientists living outside of the UK who are members of SEBBM or NVBMB. For information on this scheme and also on Biochemical Society bursaries and travel grants available for this event, click here.