It is difficult that the youngest at home are not victims of discouragement and boredom at some point during the confinement we are experiencing. They are continuously listening to news about the Covid-19 disease: infected, asymptomatic, confinement, research, vaccines, deaths, etc. However, they know little about this coronavirus so special for them.
The experience that I proposed to my 9 years old daughter helped us to better understand the SARS-CoV-2 virus through its structure. To know about its "physical appearance" would help us better understand how it acts.
The proposed activity was carried out collaboratively in the family. First, I introduced her to the virus world with the Spanish translation of Arthur Kornberg’s tale Germ Stories1,2. Afterwards, we did an internet search for images of the new virus, choosing reliable pages. Once we found what its “appearance” was, we set down to work. For this, we used a hollow plastic ball (which had contained a gift inside), modelling clay of different colors, brushes and fixing varnish.
The wrapping of the virus is done by surrounding the two halves of the ball with modelling clay. With modelling clay of other colors, the spikes and the rest of the envelope proteins were formed. All of them were glued on the envelope. For the genetic material, the single-stranded RNA, a thin cylinder of modelling clay was used, to which balls of modelling clay were attached representing the nucleocapsid proteins. Finally, all the structures were varnished. When they were dry, the RNA was placed inside and the two halves were joined.
1. Cuentos de microbios. Arthur Kornberg. Editorial Reverté. Barcelona. 2012.
2. Germ Stories. Arthur Kornberg. University Science Books. Mill Valley. 2007.
Authors: Candela Morales-Bajo and Ana M. Bajo
Join the FEBS Network today
Joining the FEBS Network’s molecular life sciences community enables you to access special content on the site, present your profile, 'follow' contributors, 'comment' on and 'like' content, post your own content, and set up a tailored email digest for updates.
A remarkable job!
Bravo, Ana and Candela!
Great to interest children in Biochemistry!.