Jim's View - From basic science to transformative outcomes: how can we make it sustainable?
There are many means by which the results of our scientific enterprise provide a public good that well‐justifies the expense involved.
Nobel Laureate James Rothman discusses this in a series of three Jim's View articles published in FEBS Letters. The first essay ("Why basic science?") takes a broad historical view of the extraordinary impact that the basic medical sciences have had on the human condition over the past century. The next essay ("What makes transformative science possible?") attempts to identify the key ingredients that enable scientists to produce transformative outcomes, focusing on the decades of fundamental research into cholesterol that yielded the statin drugs to control high blood cholesterol, and thus the risk of atherosclerosis.
The final essay in this series ("Patience vs urgency") appraises the prospects and challenges for sustaining such productive basic sciences in current societal environments.
We trust that these three articles, addressed to the scientific community as a whole, will provide food for thought in particular to policy makers and funding agencies as they address one of the most contemporary debates in modern science.
Read the articles: