Editor's Choice Articles - October 2020

Every issue we select one outstanding article as The FEBS Journal's Editor's Choice, this is made freely available to read. Here, we summarise the chosen article within our October issue. Click on the link to access the paper for free!
Editor's Choice Articles - October 2020

Glycosylation of hyperthermostable designer cellulosome components yields enhanced stability and cellulose hydrolysis

Enzymatic breakdown of cellulose is a major challenge in the production of second‐generation biofuels. Hyperthermostable enzymes from Caldicellulosiruptor bescii, a very efficient cellulolytic bacterium, were assembled into highly active cellulose deconstruction complexes: designer cellulosomes.

We transformed Ca. bescii to produce designer cellulosomes composed of glycosylated scaffoldins and chimaeric Ca. bescii enzymes. This study demonstrated that glycosylation on these designer cellulosomes improved their thermostability and activity.

Read the Original Article here: https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15251

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