The Berlin Institute of Health (BIH) is a biomedical research institution focusing on translational research and precision medicine. BIH uses a systems medicine approach to develop innovative options for prediction, prevention and advanced therapies for progressive diseases in order to improve patients’ health and quality of life. To realize its innovative plans in translational research, BIH builds on the strengths and expertise of its founding institutions Charité – Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC).