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Glycobiology

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I am a Professor of Toxicology, Biochemistry and Cell Signaling at Université Paris Cité (former Université Paris Descartes). I have completed my PhD in molecular toxicology and a post-graduate year in Bethesda, MD. I am the head of a Master degrees in toxicology and ecotoxicology. My research is based on cellular and animal models and on three main axes: 1) the influence of persistent organic pollutants on breast tumorigenesis and metabolic disruption, 2) the contextual role of pollutants in the occurrence of chronic liver diseases including steatosis and fibrosis, 3) the effect of mixtures on the progression of neurodegenerative diseases. I am involved in the development of innovative pedagogy methods and technics in order to improve transmission, acquisition, memorization and utilization of scientific knowledge by our biomedical students. I used flipped classrooms, quizzes (at home and during courses) and virtual reality to interact and immerge with students in and outside the classroom. Indeed, I developed with pedagogic engineers, 1) Home-based 45’’ Quizzes to engage students in regular learning modes and 2) serious games on cell signaling and xenobiotic stress. Together, with Etienne Blanc, Caroline Chauvet and Frédéric Dardel, I wrote several French books of biochemistry and toxicology topics for undergraduate students. I collaborate with several national and international institutes and universities (CNAM Thierry KOSCIELNIAK, Université de Strasbourg Jean-Luc SOUCIET, National University of Singapore, Fun Man FUNG...) for the development of innovative methods in teaching.

Dr. Irene Díaz-Moreno is Full Professor of Biochemistry and Molecular Biology at the Institute of Chemical Research of the Scientific Research Centre Isla de la Cartuja – cicCartuja, in Seville (Spain). She was awarded with her Ph.D. with European mention from the University of Seville in 2005. Dr. Irene Díaz-Moreno has worked in collaboration with groups at the Universities of Göteborg (Sweden) and Leiden (The Netherlands) on molecular recognition between metalloproteins involved in electron-transfer processes. She was an EMBO postdoctoral fellow (2006–2008) at the NIMR-MRC in London (UK), working on the regulatory mechanisms of mRNA decay by RNA-binding proteins. In 2010, she got a permanent position at the University of Seville, where she is developing research projects on Biointeractomics field, as well as on the post-translational regulation of biological macromolecules.

I am a molecular biophysicist applying single-molecule fluorescence spectroscopy and advanced fluorescence microscopy techniques as well as tailoring new techniques and integrating with other experimental and theoretical techniques to study biomolecular interactions, structure, and dynamics in solution and the cell. I have been implementing my knowledge and experience in performing experiments to answer questions regarding various biomolecular systems, such as Adenylate Kinase, the bacterial transcription initiation complex, p53, the amyloid-beta peptide, alpha-synuclein, and more. Since I opened my lab in 2018, I have been interested in the molecular etiology of a group of diseases called Synucleinopathies (e.g., Parkinson's disease). My interests include, but are not limited to (i) the structure-dynamics-function relationship in intrinsically disordered proteins (IDPs); (ii) phase-separated bio-condensates in health and disease; (iii) sensitive detection of bio-nanoparticles, such as viruses, exosomes, and IDP-based oligomers/aggregates. 

Currently Honorary Professor of the Free University of Brussels (ULB) Medical Faculty, Belgium. Besides 35 years of basic and translational medical research, I also spent 4 years in industry as head of the Molecular Biology lab at Baxter Healthcare research facility in Belgium. I spent 10 years supervising and managing Biochemistry wet labs and thereafter 15 years teaching Molecular Biology to medical, biomedical and veterinary students (BA2) but also to Biomedical Civil Engineers (MA1).I also supervised or co-supervised PhDs, MD clinician-researchers and 40 Biomedical and Medical Master's theses.  I am currently President of the Belgian Society for Biochemistry and Molecular Biology. I have been with FEBS since 2003 as a member of the FEBS Education Working Group and then Committee, and after 2012 actively contributing to FEBS education activities such as presenting talks and workshops on various topics and YSF. LBPN Lab Web Pages Publications-Scholar

I am an Associate Professor at the Department of Biochemistry and Clinical Analysis at the Faculty of Pharmacy, University of Sarajevo. My research interest in general is the area of genetics of type 2 diabetes, obesity and metabolic syndrome, pharmacogenetics of diabetes, association of inflammatory biomarkers and free fatty acids with diabetes, obesity and metabolic syndrome.

My research interests focus on the roles mitochondria play in aspects of eukaryotic life, ranging from their origin, metabolism, biogenesis and role they play in cell death pathways. These are interrogated using biochemical, molecular biology, genetic and cell biology techniques. I incorporate these interests into classes I teach to provide an understanding of practical techniques and also the current literature in the field. I studied biochemistry at the University of Leeds, with an industrial placement at Astra Charnwood, followed by a PhD at the University of Bristol, supervised by Professor Andrew Halestrap, to characterise the molecular composition of the mitochondrial permeability transition pore, with support from MitoKor. My post-doctoral training on the mitochondrial pathway of apoptosis supervised by Dr Doug Green was at the La Jolla Institute of Allergy and Immunology in San Diego, California and St Jude Children's Research Hospital in Memphis, Tennessee. I then was an associate research scientist working in the laboratory of Professor Alexander Tzagoloff at Columbia University in New York to study biogenesis of mitochondrial cytochrome c oxidase in budding yeast, Saccharomyces cerevisiae. I held independent positions as assistant professor at the New York Institute of Technology in New York and Staffordshire University in Stoke-on-Trent where I continued my research and taught subjects related to biochemistry, cell biology, genetics and molecular biology. I am now a senior lecturer in biotechnology at Liverpool John Moores University.  I am a strong supporter of scientific communications and outreach to disseminate scientific developments and knowledge to a broader audience with the goal of increasing the general support of the scientific process. I also direct Biomed News, a free biomedical research literature discovery platform that uses machine learning.