This short video shows Chedi Erradhouani and Xavier Coumoul, two of the authors from a recent FEBS Open Bio review on metabolic disrupting chemicals, briefly introducing the role of these substances in the etiology of metabolic pathologies such as obesity, diabetes, and hepatic steatosis. They also highlight the importance of the intestine in metabolism and the role of the zebrafish as an alternative model for investigating the effect of pollutants in the intestine.
The review was published in the In the Limelight: Toxicology special issue (Volume 14, Issue 9) in FEBS Open Bio, guest edited by Frank Michelangeli. This “In the Limelight” issue features three Review articles, and highlights current research and future directions in the field of environmental toxicology of some organic pollutants, in relation to human health and disease.
Erradhouani, C., Bortoli, S., Aït-Aïssa, S., Coumoul, X. and Brion, F. (2024), Metabolic disrupting chemicals in the intestine: the need for biologically relevant models. FEBS Open Bio, 14: 1397-1419. https://doi.org/10.1002/2211-5463.13878
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I have worked with zebrafishes and toxicology with EDCs for a while. Such a nice content <3