INFRAFRONTIER, the European Research Infrastructure for Modelling Human Diseases, is a non-profit organisation dedicated to advancing the understanding and treatment of diseases through cutting-edge in-vivo and in-vitro models. Operated by a network of over 20 leading biomedical research institutes, it empowers research on human health and disease while committing to excellence and prioritising animal welfare. By collaborating with other infrastructures, INFRAFRONTIER fosters global data sharing and plays a vital role in addressing major health challenges.