Our lab uses genetically modified mouse models and a combination of cell biology, molecular biology, and biochemistry techniques to study the role of altered mitochondrial dysfunction and metabolism in human diseases. A primary analytical tool of the group is metabolomics, which enables the parallel quantification of hundreds of small molecule metabolites. The team also uses computational approaches to integrate datasets from multi-dimensional analyses, including metabolomics, proteomics, and transcriptomics, with the aim to model aging-related disorders and to generate mechanistic hypotheses that will be cross validated experimentally.
Launched in 2011, FEBS Open Bio is an online-only open access journal for the rapid publication of research articles in molecular and cellular life sciences in both health and disease. The journal's peer review process focuses on the technical soundness of papers, leaving the assessment of their impact and importance to the scientific community.
Dr Emma Yhnell is a Senior Lecturer in Neuroscience at Cardiff University, Wales, UK.
A multi-award-wining scientist, committed change-maker and innovative educator, Emma’s unique approach to teaching uses her international experience in science communication to communicate complex topics effectively, actively engaging, enthusing and entertaining her learners.