I am Dr. Attaur Rahman from Pakistan, did my bachelor as Doctor of Veterinary Medicine (DVM) (Gold Medalist), MPhil in Veterinary Physiology and Biochemistry (Gold Medalist) from Sindh Agriculture University (SAU) Tandojam Pakistan. I have earned my PhD in Medical Sciences specialized in Cardiovascular Physiology from the Centre for Cardiovascular Genomics and Medicine (CCGM), Department of Medicine and Therapeutics (MEDT), Faculty of Medicine, The Chinese University of Hong Kong (CUHK), Hong Kong. Currently, I am perusing my Postdoctoral Research Fellowship (Postdoc) training in Mitochondrial Biology in CCGM, MEDT, CU Medicine at the CUHK Hong Kong. I am a cardiovascular physiologist and mitochondrial biologist, and my research is focused on inter mitochondrial communication (IMC) and innovative role of mitochondrial dynamic (MD) and mitochondrial nanotunnels (MNTs) in mediating cardioprotection against Ischemia Reperfusion Injury (IRI)-induced ST Segment Elevated Myocardial Infarction (IRI-STEMI). I am keenly interested in altered cardiac mitochondrial morphology (shape, size, positioning and motility) and novel compensatory physiological mechanisms of mitochondrial nanotunneling in cardiomyocytes during the course of development of MI and genetic and pharmacological manipulation of MNTs to find out some therapeutic avenues. In addition, I am particularly interested in Intermitochondrial Communication (IMC), Mitochondrial Quality Control (MQC) mechanisms and Artificial Mitochondrial Transfer and Transplantation (AMTT) therapy including horizontal and vertical mitochondrial transfer in settings of cardiovascular diseases, neurodegenerative diseases (AD, PD, HD, ALS) and Tumor Microenvironment (TME). Besides this, I am also avidly interested in Assisted Reproductive Techniques (ART) particularly IVF, ICSI, ASFI, ET and Mitochondrial Replacement Therapy (MRT) for rare mitochondrial diseases.

Biochmeistry Graduate|Research Enthusiast

Our lab uses genetically modified mouse models and a combination of cell biology, molecular biology, and biochemistry techniques to study the role of altered mitochondrial dysfunction and metabolism in human diseases. A primary analytical tool of the group is metabolomics, which enables the parallel quantification of hundreds of small molecule metabolites. The team also uses computational approaches to integrate datasets from multi-dimensional analyses, including metabolomics, proteomics, and transcriptomics, with the aim to model aging-related disorders and to generate mechanistic hypotheses that will be cross validated experimentally.