FEBS Open Bio is celebrating its 10th anniversary

FEBS Open Bio is celebrating its 10th anniversary with a special issue of editorials, reviews, and research articles, all especially commissioned for the occasion. Read about the exciting content here.
FEBS Open Bio is celebrating its 10th anniversary

This month, FEBS Open Bio celebrates its 10th birthday with a special anniversary issue containing a diverse selection of cutting-edge reviews, research articles, and editorials, all especially commissioned for the occasion. We invite you all to join the celebrations by checking out the contents of this issue below. We are sure there is something to interest everyone in the virtual pages of the issue, and thank all our authors, reviewers, editors, and authors for a very successful and productive decade!

Editorials:

  • Ten years of FEBS Open Bio – Duncan E. Wright and Miguel A. De la Rosa

In this editorial, the journal’s Editor-in-Chief and Editorial Manager summarise the history of the journal and introduce the contents of the 10th anniversary issue.

  • FEBS Open Bio: past, present, and future - Duncan E. Wright, Felix M. Goni, Mary Purton, Laszlo Fesus, Johannes Buchner, John Mowbray and Miguel A. De la Rosa

In celebration of the 10th anniversary issue of FEBS Open Bio, we spoke to some of the key figures of the journal’s genesis, development, and its future direction, and recount here their thoughts and experiences.

  • Learning objectives: an epiphany – Priscilla Soulié and Pierre Cosson

An editorial describing the use of learning objectives in the creation of a new Bachelor-Master curriculum in Biomedical Sciences at the University of Geneva in 2017, which will be of enormous interest to all educators.

Review articles:

  • The structure of gangliosides hides a code for determining neuronal functions

        Giulia Lunghi, Maria Fazzari, Erika Di Biase, Laura Mauri, Elena Chiricozzi, Sandro Sonnino

 https://doi.org/10.1002/2211-5463.13197

Sandro Sonnino and colleagues at the University of Milano discuss the beginnings of the elucidation of a ganglioside ‘code’ which may regulate the physiological function of neurons, linking complex neuronal functions with biochemical diversity.

  • Evolution of memory system-related genes

Amal Bajaffer, Katsuhiko Mineta, Takashi Gojobori

        https://doi.org/10.1002/2211-5463.13224

At King Abdullah University of Science and Technology (KAUST), Takashi Gojobori and colleagues provide a broad overview of the molecular and physiological bases for memory, as well as our current understanding of its evolution.

  • Identifying sources of metabolomic diversity and reconfiguration in peach fruit: taking notes for quality fruit improvement

María F. Drincovich

https://doi.org/10.1002/2211-5463.13233

The beginning of the peach season at the Universidad Nacional de Rosario in Argentina “bore fruit” with Maria F. Drincovich’s review of metabolic diversity and reconfiguration in peach fruit.

  • Transcriptional repression shapes the identity and function of tissue macrophages

Krisztian Bene, Laszlo Halasz, Laszlo Nagy

https://doi.org/10.1002/2211-5463.13269

Laszlo Nagy and colleagues at Johns Hopkins All Children's Hospital, Florida and the University of Debrecen review transcriptional repressors that modulate macrophage function and development.

  • A brief overview of BNIP3L/NIX receptor-mediated mitophagy

Mija Marinković and Ivana Novak

https://doi.org/10.1002/2211-5463.13307

This mini-review by Ivana Novak and colleagues at the University of Split describes the role of the mitophagy receptor BNIP3L/NIX in the development of certain cell types.

  • The interplay between pathogens and Atg8 family proteins: thousand-faced interactions

Dávid Tóth, Gábor V. Horváth and Gábor Juhász

https://doi.org/10.1002/2211-5463.13318

Gábor Juhász and colleagues at Eötvös Loránd University describe the use of prediction software to identify LIR motifs within SARS-CoV-2 proteins and Atg9 proteins. This offers a timely example of xenophagy in terms of the interactions between proteins of different pathogens.

  • Molecular mechanisms of the influenza fusion peptide: Insights from experimental and simulation studies

Diana Lousa and Cláudio M. Soares

https://doi.org/10.1002/2211-5463.13323

Diana Lousa and Cláudio M. Soares of NOVA University Lisbon review findings of experimental and computational studies of the influenza fusion peptide structure, mode of action, and key residues.

  • Bacterial phospholipases C with dual activity: phosphatidylcholinesterase and sphingomyelinase

Laura Monturiol-Gross, Fabian Villalta-Romero, Marietta Flores-Díaz, Alberto Alape-Girón

https://doi.org/10.1002/2211-5463.13320

Alberto Alape-Girón and colleagues at Universidad de Costa Rica and Instituto Tecnológico de Costa Rica discuss structural aspects of bacterial phospholipase C proteins which exhibit dual enzymatic activities.

Research articles: 

  • Extracellular RNA transfer from non-malignant human cholangiocytes can promote cholangiocarcinoma growth

Yu Ota, Kenji Takahashi, Shin Otake, Yosui Tamaki, Mitsuyoshi Okada Irene Yan, Kazunobu Aso, Satoshi Fujii, Tushar Patel,  Masakazu Haneda

https://doi.org/10.1002/2211-5463.13294

Tushar Patel et al. show extracellular vesicles can promote the growth of cholangiocarcinoma through the transfer of microRNA.

  • Caffeic acid: an antioxidant with novel antisickling properties

Tigist Kassa, James G. Whalin, Mark P. Richards and Abdu I. Alayash 

https://doi.org/10.1002/2211-5463.13295

Abdu I. Alayash et al. report on antisickling properties of the antioxidant caffeic acid with potential for sickle cell disease treatment.

  • Improvement of image resolution by combining enhanced confocal microscopy and quantum dot triexciton imaging

Simon Hennig, Dietmar J. Manstein

https://doi.org/10.1002/2211-5463.13246

Dietmar Manstein and his colleague Simon Hennig of Hannover Medical School demonstrate quantum dot triexciton imaging with laser scanning microscopy can increase lateral and axial resolution.

  • Structural and functional insights into lysine acetylation of cytochrome c using mimetic point mutants

Inmaculada Márquez, Gonzalo Pérez-Mejías, Alejandra Guerra-Castellano, José Luis Olloqui-Sariego, Rafael Andreu, Juan José Calvente,  Miguel A. De la Rosa, Irene Díaz-Moreno

https://doi.org/10.1002/2211-5463.13284

Irene Díaz-Moreno and colleagues at the University of Seville report that acetylation of lysines 8 and 53 in cytochrome c  are crucial for thermal stability and function, illuminating cytochrome c extra-mitochondrial roles.