Theresia Stradal - Cytoskeletal remodeling during infection: A tale of Salmonella et al.

Like

Share this post

Choose a social network to share with, or copy the URL to share elsewhere

This is a representation of how your post may appear on social media. The actual post will vary between social networks

Remodeling of the actin cytoskeleton is involved in all motile and membrane trafficking processes, including cell migration, phagocytosis, macropinocytosis, endocytosis, exocytosis, and last, not least autophagy. This explains why actin and actin polymerization regulators constitute prime targets of bacterial pathogens, which have evolved to manipulate signaling pathways to actin cytoskeleton remodeling at various key nodes, foremost upstream Rho GTPase signaling, but also downstream actin polymerization and depolymerization factors. In my talk, I will address the molecular mechanisms of host cell responses to well-characterized Salmonella enterica virulence factors, including members of the Sop (Salmonella outer protein) family of proteins translocated into the host, and from there move on to less well understood mediators of bacterial pathogenesis and effects. 

Join the FEBS Network today

Joining the FEBS Network’s molecular life sciences community enables you to access special content on the site, present your profile, 'follow' contributors, 'comment' on and 'like' content, post your own content, and set up a tailored email digest for updates.