Research Interest

Biotechnology Chemical Biology Computational Biology Drug Design Enzymology Genome Organization and Stability Metabolism Metabolomics Microbiology Protein Chemistry Protein Engineering Protein Expression Protein Structure/Modifications

FEBS Constituent Society

Romania (RSBMB)

Other Expertise/Interests

Grant writing Journal publishing Postgraduate training Scientific communication Undergraduate teaching

Followed by

Popular contributions

3D Printed model of DNA-Sequencing Nanopore

EDUCATOR

3D Printed model of DNA-Sequencing Nanopore

Marius Mihasan

Oct 15, 2021

3D printing as a cheap way of creating macromolecular models usable for teaching

EDUCATOR

3D printing as a cheap way of creating macromolecular models usable for teaching

Marius Mihasan

Sep 03, 2021

FEBS Network special areas

Channels contributed to:

EDUCATOR

Recent Comments

Comment on 3D Printed model of DNA-Sequencing Nanopore

Marius Mihasan

Oct 19, 2021

Replying to Angel Herráez

Great idea, Marius, and very good looking. thinking of the slice and magnets is wonderful.

May I ask how did you model the DNA piece?

That was a bit tricky and is not modeled as you might expect. The part that goes through the pore is PDB ID 4OCB , but after printed was slightly heated and straightened to fit. The DNA portion from the polymerase is a random sequence created in UCSF Chimera. Each strand was exported individually and after printing, one strand was slightly heated again and bent to fit the polymerase channel. Then the three parts (4OCB, the two strands of DNA) were glued together.