FEBS Junior Section present David Fernandez-Antoran

The next talk of the FEBS Junior Section in 2024 will host David Fernandez-Antoran, from the Gurdon Institute, UK and the IIS-Aragon, Spain. He will talk about epithelioids and a novel long-term 3D culture system to study tissue behaviour. The talk will be on 10 October 2024. Please share this post!
FEBS Junior Section present David Fernandez-Antoran
Like

Share this post

Choose a social network to share with, or copy the URL to share elsewhere

This is a representation of how your post may appear on social media. The actual post will vary between social networks

Update! Watch the recording of this talk.

This talk is an activity from the FEBS Junior Section, an initiative set up by students and young researchers from some of the FEBS Constituent Societies. Each month members of the FEBS Junior Section organize an online event on either a research or a career topic. This talk was coordinated by the SEBBM Junior Section (the junior section of the Spanish Society of Biochemistry and Molecular Biology, SEBBM).

Speaker: Dr David Fernandez-Antoran, from the Gurdon Institute, UK and IIS-Aragon, Spain.
Topic: “Epithelioids: A novel long-term 3D culture system to study tissue behaviour”
Time: 10 October 2024, 19:00 (CET)
For more information: See the biosketch below and visit Dr David Fernandez-Antoran's Gurdon Institute webpage and ARAID webpage.

Biosketch

I hold a PhD in molecular biology and immunology from the Spanish National Centre for Biotechnology  (Madrid, Spain). During my postdoctoral research at the MRC Cancer Unit and Wellcome Sanger Institute (Cambridge, UK), I demonstrated that low doses of ionising radiation promote the expansion of pre-existing mutant p53 clones in normal tissues. This process can be reversed through external interventions, offering significant insights into mutational landscape evolution and tumour development, and suggesting potential strategies for cancer risk reduction through chemoprevention.

In 2020, I established my own research group as a CRUK RadNet Group Leader at The Gurdon Institute, University of Cambridge. My lab focuses on cell competition mechanisms and radiation biology, utilising an innovative in vitro 3D model called Epithelioids, which I developed. This model allows for the generation of trypsin-free, ultra-long-term primary cultures of both mouse and human normal and tumour epithelia, preserving the structure, cellular heterogeneity, and clonal composition of the original tissues.

I also serve as scientific deputy director of RadNet Cambridge and co-chair of the Emerging Radiotherapy Technologies national group. In 2023, I obtained an ARAID Principal Investigator position and established a new laboratory at IIS-Aragon, Hospital Universitario Miguel Servet (Zaragoza, Spain), while continuing to lead my lab in Cambridge. This dual appointment has fostered strong scientific connections between Zaragoza and Cambridge, promoting new collaborations among researchers with shared scientific goals.

The FEBS Junior Section

Want to join this platform for young European life scientists?  Learn more about our initiative, check out the Room for the FEBS Junior Section and – if you do not have a junior section yet – read this post about how to set one up!


Photo by Irham Setyaki on Unsplash

Join the FEBS Network today

Joining the FEBS Network’s molecular life sciences community enables you to access special content on the site, present your profile, 'follow' contributors, 'comment' on and 'like' content, post your own content, and set up a tailored email digest for updates.