This talk is an activity from the FEBS Junior Section, an initiative set up by students and young researchers from some of the FEBS Constituent Societies. Each month members of the FEBS Junior Section organize an online event on either a research or a career topic.
Speaker: Dr. Adria Cañellas-Socias, Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, USA
Topic: “Tumor heterogeneity and plasticity in metastatic relapse”
Time: 19 Oct, 19:00 (CEST)
For more information: See the talk summary below and visit Dr Cañellas profile pages at Standford University School of Medicine and at IRB Barcelona.
In this seminar I will explain my PhD research in Dr Eduard Batlle’s lab at IRB Barcelona. By studying tumor heterogeneity, we uncovered the elusive identity and features of residual tumor cells that regenerate metastatic disease after curative resection of colorectal cancers (CRCs). In addition, we found that neoadjuvant immunotherapy is sufficient to prevent metastatic relapse in CRC; yet, this curative effect is restricted to a narrow temporal window as a result of a rapidly evolving immunosuppressive tumor microenvironment. In addition, I will try to integrate early career relevant aspects that I am learning along this process that may be also valuable for other young scientists.
The FEBS Junior Section
Want to join this platform for young European life scientists? Learn more about our initiative, check out the Room for the FEBS Junior Section and – if you do not have a junior section yet – read this post about how to set one up!