RESEARCH

It's About Time!—FEBS Letters' Circadian Rhythms Special Issue

FEBS Letters is pleased to announce the publication of an exciting new special issue on “Circadian clocks”, guest edited by Carrie Partch (University of California Santa Cruz, Howard Hughes Medical Institute).

FEBS Letters Mar 30, 2026

Circadian rhythms coordinate biological timekeeping on a ~ 24-h timescale, aligning physiology and behavior with the daily solar cycle on Earth. This free special issue edited by Carrie Partch features 14 review articles focusing on the latest advances in our understanding of the molecular basis of circadian rhythms, their pervasive and powerful control of biology, and new frontiers in the field, including approaches to modulate biological timekeeping to improve human health.

We invite you to read the full issue here, or view the individual articles at the links below:

Biochemical mechanism of the mammalian circadian clock

Yang Liu, Aziz Sancar

Phosphorylation of CLOCK and BMAL1—a key regulatory mechanism in the mammalian circadian clockwork

Yuta Otobe, Hikari Yoshitane

Unraveling circadian rhythms—computational insights into molecular mechanisms

Yashasvi Rao, Ashutosh Srivastava

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

Emery T. Usher, Jacqueline F. Pelham

Disorder at the heart of a molecular chronosome — insights from the fungal clock protein FRQ

Lilian Toro-Barrios, José I. Costa, Sofía Elizalde-Guerrero, Felipe Muñoz-Guzmán, Luis F. Larrondo

Time after time – circadian clocks through the lens of oscillator theory